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Side Effects of the MMRV Vaccine

Although many children do not experience problems after receiving the MMRV vaccine, side effects can still occur. Some of the most common ones include reactions at the injection site, such as pain, redness, and tenderness. In most cases, side effects are minor and easily treated. However, contact your healthcare provider immediately if serious problems occur, such as difficulty breathing or a high fever.

An Introduction to Side Effects of the MMRV Vaccine

As with all vaccines, MMRV (ProQuad®) can cause side effects. However, not everyone who receives the vaccination will have problems. Most children tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible MMRV side effects. Your healthcare provider can discuss a more complete list with you.)

MMRV Side Effects to Report

Some side effects of MMRV are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • A high fever
  • Any unusual behavior changes (aside from the usual fussiness that typically occurs after vaccinations)
  • A seizure
  • Pneumonia
  • Persistent, inconsolable crying lasting for three hours or more
  • Temporary low blood platelets (which may increase the risk of bleeding)
  • Deafness
  • Weakness, tingling, or paralysis (which may be signs of Guillain-Barré syndrome)
  • Long-term coma, seizures, or decreased consciousness
  • Permanent brain damage
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
It should be noted that many of these side effects have been reported so rarely that it is impossible to say with certainty that the problem was actually related to the vaccine.
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MMRV Vaccination Information

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